Yes. You can:
Disconnect profile(s) anytime from the Reply200 dashboard by unlinking all Business Managers or Pages using the bulk action menu.
Or remove Reply200 directly from your Facebook account:
Go to your Facebook Profile
Tap your profile picture
Select Settings & Privacy → Settings
Scroll to Business Integrations
Remove access for the Reply200 app
Once removed, all activity stops instantly — no content is lost, and you can reconnect anytime.